tecovirimat will increase the amount or effect of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Tecovirimat is a weak inhibitor of CYP2C8 and CYP2C19. Keep an eye on for adverse effects if coadministered with delicate substrates of these enzymes.tazemetostat will minimize the level or outcome of diazepam by affecti